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Genetic Tests for Non-Cancer Diseases/Conditions: A Horizon Scan

The Coverage and Analysis Group at CMS requested the Technology Assessment Program (TAP) at the Agency for Healthcare Research and Quality (AHRQ) for an update of the horizon scan of genetic tests for cancer and non-cancer diseases/conditions and with alternate year update reports on cancer and non-cancer conditions. AHRQ assigned this project to the Tufts Medical Center Evidence-based Practice Center. The current report updates genetic tests for non-cancer conditions that were identified since the 2007 horizon scan report on Genetic Testing for Non-Cancer Conditions. CMS would like the report and the accompanying database to be a ready reference for their internal discussions in this area and for decisions on future topics for systematic reviews. The main objective of this report is to provide a broad overview with sufficient information on each identified genetic test, and to provide a preliminary estimate on the amount of published literature available on each genetic test.

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