Effective for dates of service on or after May 1, 2007, CPT-4 code 88150 (cytopathology, slides, cervical or vaginal; manual screening under physician supervision) will be replaced with code 88164 (cytopathology, slides, cervical or vaginal [the Bethesda System]; manual screening under physician supervision) for the Presumptive Eligibility (PE) program. The Bethesda System is the current standard for gynecological cytology reporting.