AMA Laboratory CORRECTIONS DOCUMENT—CPT® 2013

The errata link listed below includes corrections and other information related to the CPT^® 2013 Book published by the AMA.

Pathology and Laboratory 

Tier 1 Molecular Pathology Procedures

●81161 DMD (dystrophin) (eg, Duchenne/Becker muscular dystrophy) deletion analysis, and duplication analysis, if performed*added late not in 2013 CPT book

Pathology and Laboratory

Tier 2 Molecular Pathology Procedures

â–²81401 Molecular pathology procedure, Level 2 (eg, 2-10 SNPs, 1 methylated variant, or 1 somatic variant [typically using nonsequencing target variant analysis], or detection of a dynamic mutation disorder/triplet repeat)

ADRB2 (adrenergic beta-2 receptor surface) (eg, drug metabolism), common variants (eg, G16R, Q27E)

APOB (apolipoprotein B) (eg, familial hypercholesterolemia type B), common variants (eg, R3500Q, R3500W)

EWSR1/ERG (t(21;22)) (eg, Ewing sarcoma/peripheral neuroectodermal tumor), translocation analysis, qualitative, and quantitative, if performed

EWSR1/FLI1 (t(11;22)) (eg, Ewing sarcoma/peripheral neuroectodermal tumor), translocation analysis, qualitative, and quantitative, if performed

EWSR1/WT1 (t(11;22)) (eg, Ewing sarcoma/peripheral neuroectodermal tumor), translocation analysis, qualitative, and quantitative, if performed

Revise 81401 splitting out “ADRB2” and “APOB” analytes as two separate analytes and to include the missing analyte “EWSR1/WT1…”

Pathology and Laboratory

Tier 2 Molecular Pathology Procedures

â–²81402 Molecular pathology procedure, Level 3 (eg, >10 SNPs, 2-10 methylated variants, or 2-10 somatic variants [typically using non-sequencing target variant analysis], immunoglobulin and T-cell receptor gene rearrangements, duplication/deletion variants 1 exon)

TCD@ TRD@ (T cell antigen receptor, delta) (eg, leukemia and lymphoma), gene rearrangement analysis, evaluation to detect abnormal clonal population

Revise the analyte following 81402 by removing “[TCD@]” and replacing it with “[TRD@]”.

Pathology and Laboratory

Multianalyte Assays with Algorithmic Analyses

●81503 Oncology (ovarian), biochemical assays of five proteins (CA-125, apoliproprotein apolipoprotein A1, beta-2 microglobulin, transferrin, and pre-albumin), utilizing serum, algorithm reported as a risk score

Revise the misspelled word “apolipoprotein” noted in code 81503.

Pathology and Laboratory

Multianalyte Assays with Algorithmic Analyses

●81506 Endocrinology (type 2 diabetes), biochemical assays of seven analytes (glucose, HbA1c, insulin, hs-CRP, adoponectin adiponectin, ferritin, interleukin 2-receptor alpha), utilizing serum or plasma, algorithm reporting a risk score

Revise the misspelled word “adiponectin” noted in code 81506.

Pathology and Laboratory

Transfusion Medicine

86890 Autologous blood or component, collection processing and storage; predeposited

86891 intra- or postoperative salvage

(For physician services to autologous donors, see 99201-99204)

Delete the parenthetical note following 86891.

Updates to Appendix O Multianalyte Assays with Algorithmic Analyses