Precision Medicine Regulatory Research Roadmap Set Out In Perspective Article

A recent perspectives article appearing in Science Translational Medicine described several regulatory research challenges that remain in the way of fulfilling the diagnostic testing potential of next-generation sequencing. Stanford University’s Russ Altman and his colleagues outlined nine main challenges that must be tackled if next-generation-based diagnostic testing, under the broader umbrella of the Precision Medicine Initiative, is to become routine. The team highlighted the need for systems to store genomic data and related software tools in a manner that’s secure, but allows for data sharing when needed. It also touched on the importance of accurately comparing error models and pipelines for different next-generation technologies, as well as coming up with validated reference data sets and standards for clinical variant database use. It will be necessary to establish appropriate population-based frameworks for interpreting genetic variants in the clinical context, along with effective strategies for returning genetic information to physicians and patients in way that’s understandable and, ideally, improves care.

Source: https://www.genomeweb.com/sequencing-technology/precision-medicine-regulatory-research-roadmap-set-out-perspective-article?utm_source=SilverpopMailing&utm_medium=email&utm_campaign=Daily%20News%3A%20Precision%20Medicine%20Regulatory%20Research%20Roadmap%20Set%20Out%20In%20Perspective%20Article%20-%2004/25/2016%2003%3A50%3A00%20PM