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Study Links BRCA1/2 Germline Mutations to Platinum Drug Response in TNBC
June 4, 2018NEW YORK (GenomeWeb) – Results from a study funded by Myriad Genetics, Breast Cancer Now, and Cancer Research UK suggest that the platinum-based, DNA crosslinking chemotherapy drug carboplatin is more apt to benefit triple-negative breast cancer (TNBC) patients who carry cancer-related germline mutations in BRCA1/2 genes.