XiFin Builds on Empower CareALERTS Success with New Capabilities for Pharmacy

Announced in conjunction with National Pharmacist Day and following XiFin’s Pharmacy500 recognition, the new API-enabled solution delivers real-time immunization intelligence to help pharmacists identify unmet vaccination needs and expand clinical services

XiFin, Inc., a leader in revenue cycle management (RCM), including billing solutions enhanced with artificial intelligence (AI), today announced the expansion of its proven Empower CareALERTS™ smart clinical messaging technology, with a pharmacy-focused offering that alerts pharmacists to patient-specific vaccination opportunities directly within their existing workflows. By delivering real-time immunization alerts at the point of care, CareALERTS for Pharmacy enables pharmacists to close vaccine care gaps, engage patients more effectively, help reduce adult immunization confusion, and support broader community health needs.

Built with API-based interoperability, CareALERTS for Pharmacy integrates with pharmacy management systems, schedulers, and electronic health records, and connects to state and jurisdictional immunization registries. The solution leverages ACIP and CDC guidelines to identify patients who may be clinically eligible for vaccines and surfaces alerts in the workflow location of the pharmacy’s choosing, allowing pharmacists to act without disrupting operations.

“CareALERTS for Pharmacy is designed to meet pharmacists where they work,” said David Pope, Chief Pharmacy Officer of XiFin. “As pharmacies continue to expand their role as front-line healthcare access points, timely and actionable clinical intelligence is essential. CareALERTS empowers pharmacists to educate patients, close care gaps, and drive appropriate immunizations while improving efficiency and supporting sustainable revenue growth.”

The expansion builds on XiFin’s proven and HITRUST* i1-certified CareALERTS technology, which has been deployed in collaboration with select pharmacy customers through its medical billing solution, Empower Pharmacy Essentials. With expanded capabilities, CareALERTS is now available to a broader range of pharmacies, enabling organizations to optimize and scale immunization programs and clinical services and drive dramatic gains in pharmacy immunization performance.

2025 CareALERTS Immunization Results

In 2025, CareALERTs technology successfully increased companion immunizations by 17% among participating pharmacies, reinforcing the growing impact pharmacists have on public health. Additional real-world CareALERTs results include:

• One pharmacy chain logged over 660,000 additional immunizations in 2025
• A retail pharmacy provided an additional 232,000 immunizations to eligible but underserved patients in 2025
• One grocery chain saw an increase of over 75,000 immunizations delivered in 2025
• A supermarket realized an increase of 20,000 immunizations within its first week of implementing CareALERTS technology

The introduction of CareALERTS for Pharmacy aligns with National Pharmacist Day and XiFin’s recognition in the 2026 Pharmacy500, reflecting the company’s long-standing focus on empowering pharmacists as critical drivers of patient access and community health. Through its XiFin® Empower platform, the company supports 14 of the largest 15 U.S. retail pharmacy chains with solutions that strengthen financial performance, streamline workflows, and support pharmacists across retail, specialty, and health system settings.

2026 XiFin Pharmacy Transformation Outlook: Save the Date

In recognition of National Pharmacist Day, XiFin also announced a preview of its 2026 XiFin Pharmacy Transformation Outlook report, which will be shared during an upcoming webinar, “A Strategic Medical Billing Roadmap for 2026 and Beyond,” sponsored by Drug Store News (DSN), on February 24 at 11 AM ET.

Now in its third year, the survey and report provide an annual review of industry trends and insights into how pharmacies are navigating a rapidly evolving healthcare landscape. The 2026 report builds on feedback from nearly 1,000 respondents across the 2024 and 2025 surveys, with a focus on pharmacists’ expanding role in patient care, clinical services, and community health access.

About XiFin

XiFin is a healthcare information technology company that empowers organizations to navigate an evolving and increasingly complex healthcare landscape. The XiFin Empower platform orchestrates a variety of AI-enabled technologies and services to deliver enhanced operational efficiency, increased productivity and workflow automation. Our comprehensive set of solutions—spanning revenue cycle management, clinical workflow enablement, laboratory information systems, and patient engagement—provides healthcare organizations with the tools they need to achieve financial strength, optimize operations, and implement industry-leading strategies. XiFin Empower solutions deliver THE POWER TO DO GOOD® so that healthcare organizations can do more good for more patients. Visit www.XiFin.com, follow XiFin on LinkedIn, or subscribe to the XiFin blog to learn more.

*HITRUST is a registered trademark of the HITRUST Alliance